Nitric Acid → HCID 178428126, compound

Participants

Reaction Steps

To a solution of (−)-7-(2,5-dichlorothiophen-3-yl)-5-guanidinoimino-4-methyl-5,6,7,8-tetrahydroquinoline (0.8 g) in ethanol (20 ml) was added 1.7M nitric acid (2.3 ml), and the mixture was concentrated under reduced pressure to give crystals, which were recrystallized from water to give (−)-7-(2,5-dichlorothiophen-3-yl)-5-guanidinoimino-4-methyl-5,6,7,8-tetrahydroquinoline nitrate (Compound 116) (0.92 g).

Provenance & Evidence