Acetonitrile → HCID 18317564, compound

Participants

Reaction Steps

To a solution of 1-amino-5-(2-chlorophenyl)cyclohexen-3-one (2.0 g) in acetonitrile (50 ml) was added phenyl isothiocyanate (1.2 g), and the mixture was refluxed for 15 hours. Under reduced pressure, the solvent was evaporated, and to the residue were added ethanol (20 ml) and hydrazine hydrate (0.55 g). The mixture was refluxed for 1 hour, and under reduced pressure, the solvent was evaporated. The residue was washed with ethyl acetate to give yellow crystals of 6-(2-chlorophenyl)-3-phenylamino-4,5,6,7-tetrahydroindazol-4-one (0.8 g).

Provenance & Evidence