HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorine → 2-methyl-4,5-bis(methylsulfonyl)benzoic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorine | HCID 24526 | — |
| Reactant | 4-chloro-2-methyl-5-(methylsulfonyl)Benzoic acid | HCID 10824478 | — |
| Solvent | Sodium Perborate | HCID 517072 | — |
| Product | 2-methyl-4,5-bis(methylsulfonyl)benzoic Acid | HCID 11266313 | — |
Reaction Steps
in stage c) the chlorine substituent is converted into a second methylsulfonyl group by reacting 2-methyl-4-chloro-5-methylsulfonylbenzoic acid with sodium methylthiolate and then oxidizing the thioether with an oxidizing agent, in particular sodium perborate, to give the corresponding intermediate 2-methyl-4,5-di(methylsulfonyl)benzoic acid,
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06350904B1 |
| Source dataset | uspto-grants-2002_02 |
| ORD ID | ord-dd5b7f99c54e43c696ffb1167c41a27e |
| Source note | uspto-grants-2002_02 |