1-Iodododecane → 3-[Dodecyl(methyl)amino]propan-1-OL

HRID 1700876Notes

Reaction equation

HRID 1700876 reaction equation
[CH3:1][NH:2][CH2:3][CH2:4][CH2:5][OH:6].I[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19]>>[CH2:8]([N:2]([CH2:3][CH2:4][CH2:5][OH:6])[CH3:1])[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19]

Participants

3

Reactant 2

HCID 202821-IodododecaneHCID 101489863-(Methylamino)-1-propanol

Product 1

HCID 131222613-[Dodecyl(methyl)amino]propan-1-OLYield 96%

Procedure

A solution of 3-(methylamino)propanol (5.71 g, 64.0 mmol, S. Koepke, R. Kupper, and C. J. Michejda, J. Org. Chem., 44, 2718,1979)), and iodododecane (7.58 g, 25.6 mmol) was reacted as described in example 1 to give 6.33 g (96%) of the title material as an oil, b.p. 100-105° C./0.04 torr.

Sources & evidence

ORD record
ord-21879c34c41243e6a2c2f4986c2992ea
Source dataset
uspto-grants-2002_02
Patent number
US06350892B1

Reaction notes

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