HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 3-[4-[2-(N-Dodecyl-N-methylamino)ethoxy]-2-methoxyphenyl]propanoic acid, methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | 3-[4-[2-(N-Dodecyl-N-methylamino)ethoxy]-2-hydroxyphenyl]propanoic acid, methyl ester | HCID 86757116 | — |
| Product | 3-[4-[2-(N-Dodecyl-N-methylamino)ethoxy]-2-methoxyphenyl]propanoic acid, methyl ester | HCID 86757117 | 91.6% |
Reaction Steps
3-[4-[2-(N-Dodecyl-N-methylamino)ethoxy]-2-hydroxyphenyl]propanoic acid, methyl ester (500 mg, 1.18 mmol) and methanol (0.096 ml, 2.37 mmol) were reacted under Mitsunobu conditions as described in example 1 and afforded the title compound (471 mg, 81%) as a pale yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06350892B1 |
| Source dataset | uspto-grants-2002_02 |
| ORD ID | ord-592052d2b8b84cbaadb7a8a20a131143 |
| Source note | uspto-grants-2002_02 |