Acetone → HCID 54365370, compound

Participants

Reaction Steps

Aqueous sodium hydroxide (28.1 ml; 10%) is added dropwise, rapidly, to a stirred mixture of p-(1,1,2,2-tetrafluoroethoxy)benzaldehyde (11 ml; 0.069 mole), acetone (2.4 ml; 0.33 mole), absolute alcohol (135 ml) and water (14 ml). The reaction mixture exotherms to 30° C. The reaction mixture is then cooled, the precipitated material is filtered, washed and dried to afford 3.8 g (25%) of title product.

Provenance & Evidence