Acetone → HCID 54244609, compound

Participants

Reaction Steps

A mixture of p-difluoromethoxybenzaldehyde (10.7 g; 0.0622 mole), acetone (2.2 ml; 0.0296 mole, ethanol (103 ml) and water (10 ml) is added dropwise, rapidly, and with stirring to an aqueous sodium hydroxide solution (25.5 ml; 10%). The reaction mixture exotherms to 30° C. and a precipitate forms. The precipitate is filtered, washed and dried to afford 9.0 g (97.2%) of title product.

Provenance & Evidence