Methylamine → 2-Nitro-6-methylaminobenzonitrile

HRID 1701229Notes

Reaction equation

[N+:1]([C:4]1[CH:11]=[CH:10][CH:9]=[C:8]([N+:12]([O-])=O)[C:5]=1[C:6]#[N:7])([O-:3])=[O:2].[CH3:15]N>>[N+:1]([C:4]1[CH:11]=[CH:10][CH:9]=[C:8]([NH:12][CH3:15])[C:5]=1[C:6]#[N:7])([O-:3])=[O:2]

Participants

Reactant 2

HCID 6329Methylamine

HCID 520718Dinitrobenzonitrile

Product 1

HCID 127157712-Nitro-6-methylaminobenzonitrile

Procedure

2-Nitro-6-methylaminobenzonitrile is prepared from 2,6-dinitrobenzonitrile as in Example 10 using methylamine instead of N-methylpiperazine, m.p. 203°-206°.

Sources & evidence

ORD record: ord-b2e0e437a24f4bc1abec0ea31d5f28c0
Source dataset: uspto-grants-1980_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04191840

Reaction notes

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