HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hexane → Ethyl 2-cyano-3-(5-n-butyl-2-pyridylamino)acrylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hexane | HCID 8058 | — |
| Reactant | 2-Propenoic acid, 2-cyano-3-ethoxy-, ethyl ester | HCID 78943 | — |
| Reactant | 5-Butylpyridin-2-amine | HCID 18428650 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | Ethyl 2-cyano-3-(5-n-butyl-2-pyridylamino)acrylate | HCID 70514903 | — |
Reaction Steps
A solution of 2-amino-5-n-butylpyridine (3.72 g., 23.43 mmoles) and ethyl ethoxymethylenecyanoacetate (3.96 g., 23.43 mmoles) in toluene was heated for 10 minutes by means of an oil bath maintained at 100°. The solution was cooled and treated with Skellysolve B (200 ml.). The mixture was triturated for 18 hours at room temperature and then filtered. The collected title compound (4.3 g., 67.2%) had m.p. 69°-73°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04192944 |
| Source dataset | uspto-grants-1980_03 |
| ORD ID | ord-bef42e2dcac442f4a4680cca8b943415 |
| Source note | uspto-grants-1980_03 |