Dichloromethane → 2-[4-(2-Butylbenzimidazol-1-yl)methylphenyl]benzoic acid

HRID 170149Notes

Reaction equation

HRID 170149 reaction equation
[CH2:1]([CH2:2][CH2:3][CH3:4])[c:5]1[n:6][c:7]2[c:8]([n:9]1[CH2:10][c:11]1[cH:12][cH:13][c:14](-[c:17]3[c:18]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[cH:19][cH:20][cH:21][cH:22]3)[cH:15][cH:16]1)[cH:30][cH:31][cH:32][cH:33]2.[CH2:41]([Cl:42])[Cl:43].[OH:34][C:35]([C:36]([F:37])([F:38])[F:39])=[O:40]>>[CH2:1]([CH2:2][CH2:3][CH3:4])[c:5]1[n:6][c:7]2[c:8]([n:9]1[CH2:10][c:11]1[cH:12][cH:13][c:14](-[c:17]3[c:18]([C:23](=[O:24])[OH:25])[cH:19][cH:20][cH:21][cH:22]3)[cH:15][cH:16]1)[cH:30][cH:31][cH:32][cH:33]2

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 67572640Tert.butyl 4'-[(2-n-butyl-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate

Product 1

HCID 41100262-[4-(2-Butylbenzimidazol-1-yl)methylphenyl]benzoic acid

Sources & evidence

ORD record
ord-8cf70e6ef5fe46a8a309dd5718a410d7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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