反应详情

A solution containing 22 g. of ethyl phenylpyruvate, 65 g. of acetic anhydride and 20 mg. of p-toluenesulfonic acid monohydrate was refluxed for 2.5 hours. Excess acetic anhydride was stripped from the reaction mass and the product, crude (Z)-ethyl 2-acetyloxy-3-phenyl-2-propenoate, was distilled at about 1.6 mm. Hg. (b.p. 120°-135° C.). The recovered product crystallized on standing in refrigeration and was recovered by filtration and recrystallized from ethanol; recovered 12.1 g., m.p. 41°-47° C.; second recrystallization, 10.5 g., m.p. 47°-49° C.; third recrystallization, 9.2 g., m.p., 47°-49° C.

1. additionA solution containing 22 g
2. distillationthe product, crude (Z)-ethyl 2-acetyloxy-3-phenyl-2-propenoate, was distilled at about 1.6 mm. Hg
3. customThe recovered product crystallized
4. filtrationwas recovered by filtration
5. customrecrystallized from ethanol
6. customrecovered 12.1 g
7. customsecond recrystallization, 10.5 g
8. customthird recrystallization, 9.2 g
9. customm.p., 47°-49° C.