Dimethylformamide → 4-Aminobenzaldehyde

HRID 1701694Notes

Reaction equation

HRID 1701694 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([CH3:10])=[CH:6][CH:5]=1)([O-])=O.C(#N)C.CN(C)C=[O:17]>>[NH2:1][C:4]1[CH:9]=[CH:8][C:7]([CH:10]=[O:17])=[CH:6][CH:5]=1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 6342AcetonitrileHCID 74734-Nitrotoluene

Product 1

HCID 111584-Aminobenzaldehyde

Procedure

The procedure of Example 1 was followed except that 2.3 g (3.4 wt.% of the p-nitrotoluene) of acetonitrile were substituted for the N,N-dimethylformamide, to obtain 37.7 g (0.312 mol) of p-aminobenzaldehyde and then obtain 38.5 g (0.315 mol) of p-hydroxybenzaldehyde.

Sources & evidence

ORD record
ord-3d40b43dba7c4b07a800b564f2a22480
Source dataset
uspto-grants-1980_03
Patent number
US04195041

Reaction notes

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