反应详情

Methylmercaptan is introduced into a solution of 14 g of 5-hydroxymethyluracil in 80 ml of trifluoroacetic acid over the course of one hour until saturation is reached, the temperature being kept at 25° C. The solution is then left to stand for 2 hours, the solvent is evaporated under reduced pressure and the residue is crystallised from glacial acetic acid. 5-Methylthiomethyluracil is obtained as colourless crystals of melting point 239°-241° C.

1. custombeing kept at 25° C
2. waitThe solution is then left
3. customthe solvent is evaporated under reduced pressure
4. customthe residue is crystallised from glacial acetic acid