Methyl iodide → HCID 178482391, compound

HRID 1701791Notes

Reaction equation

HRID 1701791 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([CH:10]=[C:11]2[N:15]([CH3:16])/[C:14](=[N:17]\[H])/[N:13]([CH3:19])[C:12]2=[O:20])=[CH:2]1.[CH3:21]I>CO>[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([CH:10]=[C:11]2[N:15]([CH3:16])/[C:14](=[N:17]\[CH3:21])/[N:13]([CH3:19])[C:12]2=[O:20])=[CH:2]1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 178506455HCID 178506455, compound

Product 1

HCID 178482391HCID 178482391, compoundYield 20.3%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

500 mg of (E)-5-(indol-3-ylmethylene)-1,3-dimethyl-2-imino-4-imidazolidinone are refluxed in methanol for 24 hours with 425 mg of methyl iodide. The product is chromatographed on silica gel and alumina. There are obtained 107 mg of (E)-5-(indol-3-ylmethylene)-1,3-dimethyl-2-methylimino-4-imidazolidinone.

Workup

  1. customThe product is chromatographed on silica gel and alumina

Sources & evidence

ORD record
ord-84c3523a74dc40eb901cdaaae79c039e
Source dataset
uspto-grants-1980_03
Patent number
US04195179

Reaction notes

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