2-Fluorobenzoyl chloride → HCID 70586839, compound

Participants

Reaction Steps

A mixture of 2-fluorobenzoyl chloride, from example 4A, above, and 18.5 g (0.09 mole) of sodium saccharin is refluxed in 100 ml of tetrahydrofuran (THF) overnight. The reaction mixture is filtered hot, and the filtrate is concentrated to a partial solid/oil. The product is triturated with ether and air dried to yield 10.3 g of 2-(2-fluorobenzoyl)saccharin, m.p. 148°-151° C.

Provenance & Evidence