2,2,2-Trifluoroethyl trichloromethanesulphonate → HCID 13116877, compound

HRID 1701840Notes

Reaction equation

HRID 1701840 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[CH:12]([C:13]3[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][CH:14]=3)[NH:11][C:10]([SH:20])=[N:9]2)=[CH:4][CH:3]=1.ClC(Cl)(Cl)S(O[CH2:27][C:28]([F:31])([F:30])[F:29])(=O)=O>>[ClH:1].[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH:8]2[CH:12]([C:13]3[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][CH:14]=3)[NH:11][C:10]([S:20][CH2:27][C:28]([F:31])([F:30])[F:29])=[N:9]2)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 900272,2,2-Trifluoroethyl trichloromethanesulphonateHCID 178527834HCID 178527834, compound

Product 1

HCID 13116877HCID 13116877, compound

Procedure

By the procedure described in Example 1, 2.0 g of 4,5-bis-(4-chlorophenyl)-4,5-dihydro-1H-imidazole-2-thiol was reacted with 2,2,2-trifluoroethyl trichloromethanesulfonate to give the title compound. Recrystallization from nitromethane afforded 850 mg of colorless crystals, m.p. 230° dec. The NMR and infrared spectra were consistent with this structure.

Sources & evidence

ORD record
ord-adf3cc61b0a549a9a8f82b637e080778
Source dataset
uspto-grants-1983_04
Patent number
US04379159

Reaction notes

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