Ammonium Chloride → HCID 12875799, compound

HRID 1701847Notes

Reaction equation

HRID 1701847 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH2:7][S:8][CH2:9][CH2:10][C:11](=[NH:15])OCC.[Cl-:16].[NH4+:17]>CO>[ClH:16].[ClH:16].[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH2:7][S:8][CH2:9][CH2:10][C:11]([NH2:15])=[NH:17]

Participants

4

Reactant 2

HCID 25517Ammonium ChlorideHCID 12853022HCID 12853022, compound

Product 1

HCID 12875799HCID 12875799, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Ethyl 3-(2-pyridylmethylthio)propionimidate was reacted with an equimolar amount of ammonium chloride in methanol for 2 hours at room temperature and the product was recrystallized from a mixture of ethanol and ether to provide 3-(2-pyridylmethylthio)propionamidine dihydrochloride showing a melting point of 140°-143° C.

Workup

  1. customthe product was recrystallized from a mixture of ethanol and ether

Sources & evidence

ORD record
ord-cc53ab4d0ef64adaacbd2b74b7d34ce4
Source dataset
uspto-grants-1983_04
Patent number
US04379158

Reaction notes

Loading…