Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | HCID 13647236 | HCID 13647236 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 23318285 | HCID 23318285 | — |
Reaction Steps
172 g of 1-cyclopropylmethyl 2-[2-hydroxyethyl]pyrrolidine (1.02 mole) and 510 ml of chloroform are introduced into a 3 liter balloon flask provided with a stirrer, a reflux condenser, a thermometer and a dropping funnel. The solution is cooled to 10° C. then 151.5 g of thionylchloride (1.02 mole+25%) is dropped in while keeping the temperature between 10° and 15° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04379161 |
|---|
| Source dataset | uspto-grants-1983_04 |
|---|
| ORD ID | ord-35e76d955bb446bba94a1ffe7cdfd087 |
|---|
| Source note | uspto-grants-1983_04 |
|---|
