反应详情

Combine 4-methoxybenzyl alcohol (13.8 g, 0.10 mole) with methyl vinyl ketone (8.4 g, 0.12 mole), treat with 5 drops of concentrated sulfuric acid, and stir 1 hour. Dilute with ethyl ether, wash with 1.0 N sodium bicarbonate solution, dry the organic phase over anhydrous sodium sulfate and evaporate in vacuo to obtain the title compound, m.p. 48-9° C.

1. washwash with 1.0 N sodium bicarbonate solution
2. dry with materialdry the organic phase over anhydrous sodium sulfate
3. customevaporate in vacuo