Potassium Cation → 5-Chloro-2-(4-trifluoromethoxy-benzyl)-7-trifluoromethyl-2,3-dihydro-isoindol-1-one

HRID 170188Notes

Reaction equation

HRID 170188 reaction equation
[CH3:1][O:2][C:3]([c:4]1[c:5]([CH2:15][Br:16])[cH:6][c:7]([Cl:14])[cH:8][c:9]1[C:10]([F:11])([F:12])[F:13])=[O:17].[CH3:37][CH2:38][O:39][C:40](=[O:41])[CH3:42].[CH3:43][c:44]1[cH:45][cH:46][cH:47][cH:48][cH:49]1.[CH3:50][CH2:51][CH2:52][CH2:53][CH2:54][CH3:55].[F:18][C:19]([O:20][c:21]1[cH:22][cH:23][c:24]([CH2:25][NH2:26])[cH:27][cH:28]1)([F:29])[F:30].[K+:31].[K+:32].[O-:33][C:34]([O-:35])=[O:36]>>[C:3]1(=[O:17])[c:4]2[c:5]([cH:6][c:7]([Cl:14])[cH:8][c:9]2[C:10]([F:11])([F:12])[F:13])[CH2:15][N:26]1[CH2:25][c:24]1[cH:23][cH:22][c:21]([O:20][C:19]([F:18])([F:29])[F:30])[cH:28][cH:27]1

Participants

8

Reactant 7

HCID 813Potassium Cation2×HCID 1140TolueneHCID 8058HexaneHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 5718464-(Trifluoromethoxy)benzylamineHCID 57949559HCID 57949559, compound

Product 1

HCID 116829765-Chloro-2-(4-trifluoromethoxy-benzyl)-7-trifluoromethyl-2,3-dihydro-isoindol-1-one

Sources & evidence

ORD record
ord-da7ca86c4add4129b412a1f456b95529
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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