Pyridine → HCID 15580738, compound

HRID 1701947Notes

Reaction equation

HRID 1701947 reaction equation
[CH3:1][O:2][C:3]1[CH:11]=[CH:10][CH:9]=[C:5]([C:6]([OH:8])=[O:7])[C:4]=1N.[C:13]([O:16][C:17]1[CH:25]=[CH:24][C:20]([C:21](Cl)=O)=[CH:19][CH:18]=1)(=[O:15])[CH3:14].[N:26]1C=CC=CC=1>>[C:13]([O:16][C:17]1[CH:25]=[CH:24][C:20]([C:21]2[O:8][C:6](=[O:7])[C:5]3[CH:4]=[C:3]([O:2][CH3:1])[CH:11]=[CH:10][C:9]=3[N:26]=2)=[CH:19][CH:18]=1)(=[O:15])[CH3:14]

Participants

4

Reactant 3

HCID 1049PyridineHCID 2557202-Amino-3-methoxybenzoic acidHCID 2756254p-Acetoxybenzoyl chloride

Product 1

HCID 15580738HCID 15580738, compound

Procedure

16.7 gm (0.1 mol) of 3-methoxy-anthranilic acid were dissolved in 100 ml of pyridine, and the solution was mixed, while cooling and stirring, with 23.8 gm (0.1 mol+20%) of 4-acetoxy-benzoyl chloride. After 2 hours the reaction was finished, and the reaction mixture was poured into ice water. The crystalline precipitate thus formed was suction filtered off, dried and recrystallized from methanol.

Workup

  1. additionthe solution was mixed
  2. temperaturewhile cooling
  3. customThe crystalline precipitate thus formed
  4. filtrationfiltered off
  5. customdried
  6. customrecrystallized from methanol

Sources & evidence

ORD record
ord-87d3a34174fe4828b8e5b725614a0fee
Source dataset
uspto-grants-1983_04
Patent number
US04379788

Reaction notes

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