1-Bromo-4-chlorobutane → HCID 13072454, compound

HRID 1701951Notes

Reaction equation

HRID 1701951 reaction equation
Br[CH2:2][CH2:3][CH2:4][CH2:5][Cl:6].[OH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[N:23]([CH3:24])[C:22](=[O:25])[C:21]3[C:16](=[CH:17][CH:18]=[C:19]([O:26][CH3:27])[CH:20]=3)[N:15]=2)=[CH:10][CH:9]=1>CS(C)=O>[Cl:6][CH2:5][CH2:4][CH2:3][CH2:2][O:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[N:23]([CH3:24])[C:22](=[O:25])[C:21]3[C:16](=[CH:17][CH:18]=[C:19]([O:26][CH3:27])[CH:20]=3)[N:15]=2)=[CH:10][CH:9]=1

Participants

4

Reactant 2

HCID 813641-Bromo-4-chlorobutaneHCID 13567258183722-02-5

Product 1

HCID 13072454HCID 13072454, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

4 gm (0.014 mol) of the product in (b) were dissolved in 30 ml of dimethylsulfoxide, and the solution was mixed, while stirring, with 1.75 gm (0.014 mol+10%) of potassium tert. butylate. Subsequently, 4 ml of 1-bromo-4-chlorobutane were added, and the reaction mixture was stirred at room temperature until the reaction was complete. The reaction mixture was poured into ice water, and the crystalline precipitate thus formed was suction-filtered off, washed well with water and dried.

Workup

  1. additionthe solution was mixed
  2. customthe crystalline precipitate thus formed
  3. filtrationwas suction-filtered off
  4. washwashed well with water
  5. customdried

Sources & evidence

ORD record
ord-46a90e4647ef499792068726c329937c
Source dataset
uspto-grants-1983_04
Patent number
US04379788

Reaction notes

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