Cysteamine → HCID 20402177, compound

HRID 1702287Notes

Reaction equation

HRID 1702287 reaction equation
[CH3:1][N:2]([CH3:13])[C:3]1[O:4][C:5]([C:8](OCC)=O)=[N:6][N:7]=1.B.[NH2:15][CH2:16][CH2:17][SH:18]>>[CH3:13][N:2]([CH3:1])[C:3]1[O:4][C:5]([CH2:8][S:18][CH2:17][CH2:16][NH2:15])=[N:6][N:7]=1

Participants

4

Reactant 3

HCID 6058CysteamineHCID 6331BoraneHCID 3733789HCID 3733789, compound

Product 1

HCID 20402177HCID 20402177, compound

Procedure

When 2-dimethylamino-5-ethoxycarbonyl-1,3,4-oxadiazole [prepared according to the procedure described in Org. Magn. Resonance, 6, 144 (1974)] is hydrolyzed and reduced with borane as described in Example 58, Step A, and then is reacted with cysteamine according to the procedure described in Example 60, Step A, there is produced 2-[(2-dimethylamino-1,3,4-oxadiazol-5-yl)methylthio]ethylamine.

Sources & evidence

ORD record
ord-3022f9235e304f81b8723cbb9d191c81
Source dataset
uspto-grants-1983_04
Patent number
US04380638

Reaction notes

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