Cysteamine → HCID 20402177, compound

HRID 1702383Notes

Reaction equation

HRID 1702383 reaction equation
[CH3:1][N:2]([CH3:13])[C:3]1[O:4][C:5]([C:8](OCC)=O)=[N:6][N:7]=1.B.[NH2:15][CH2:16][CH2:17][SH:18]>>[CH3:13][N:2]([CH3:1])[C:3]1[O:4][C:5]([CH2:8][S:18][CH2:17][CH2:16][NH2:15])=[N:6][N:7]=1

Participants

4

Reactant 3

HCID 6058CysteamineHCID 6331BoraneHCID 3733789HCID 3733789, compound

Product 1

HCID 20402177HCID 20402177, compound

Procedure

When 2-dimethylamino-5-ethoxycarbonyl-1,3,4-oxadiazole [prepared according to the procedure described in Org. Magn. Resonance, 6, 144 (1974)] is hydrolyzed and reduced with borane as described in Example 58, Step A, and then is reacted with cysteamine according to the procedure described in Example 60, Step A, there is produced 2-[(2-dimethylamino-1,3,4-oxadiazol-5-yl)methylthio]ethylamine.

Sources & evidence

ORD record
ord-99fec6b7d1bc47c5a39dfd8c7042800d
Source dataset
uspto-grants-1983_04
Patent number
US04380639

Reaction notes

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