Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethyl Sulfoxide → (4-Isobutylphenyl)acetonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethyl Sulfoxide | HCID 679 | — |
| 반응물 | Sodium Cyanide | HCID 8929 | — |
| 반응물 | 1-(Chloromethyl)-4-(2-methylpropyl)benzene | HCID 181289 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | (4-Isobutylphenyl)acetonitrile | HCID 170426 | 73.4% |
반응 단계
527 g of 4-isobutylbenzyl chloride, 153 g of sodium cyanide and 720 ml of dimethylsulfoxide are agitated for 6 hours at 40° C. The mixture is cooled and then diluted with water. An oily layer separates and is extracted with ether. The ether solution is subjected to fractionation and yields 367 g of 4-isobutylphenyl acetonitrile.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04381313 |
| 출처 데이터셋 | uspto-grants-1983_04 |
| ORD ID | ord-791c4d436ca54ab2b434ceb83553cca8 |
| 출처 메모 | uspto-grants-1983_04 |