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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 170249Generated: October 29, 2026

Water → 4-(3,4-difluorophenyl)-N-[3-[4-(4-fluorophenyl)piperidin-1-yl]propyl]-5-methyl-2-oxo-1,3-oxazolidine-3-carboxamide

https://huagongshe.com/reaction/170249

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantTetrahydrofuranHCID 8028—
Reactant4-Nitrophenyl chloroformateHCID 82129—
Reactant3-(4-(4-Fluorophenyl)piperidin-1-yl)propan-1-amineHCID 10198599—
Reactant4-(3,4-Difluorophenyl)-5-methyl-oxazolidin-2-oneHCID 22048625—
ReactantButyllithiumHCID 178418339—
Product4-(3,4-difluorophenyl)-N-[3-[4-(4-fluorophenyl)piperidin-1-yl]propyl]-5-methyl-2-oxo-1,3-oxazolidine-3-carboxamideHCID 9891105—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-0286425b8ef14612bf009b67e18cff47
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)