Water → 4-(3,4-difluorophenyl)-N-[3-[4-(4-fluorophenyl)piperidin-1-yl]propyl]-5-methyl-2-oxo-1,3-oxazolidine-3-carboxamide
Reaction equation
[CH2:38]1[CH2:40][CH2:39][CH2:41][O:42]1.[CH3:16][CH2:17][CH2:18][CH2:19][Li:20].[Cl:43][C:44]([O:45][c:46]1[cH:47][cH:48][c:49]([N+:50]([O-:51])=[O:52])[cH:53][cH:54]1)=[O:55].[F:1][c:2]1[cH:3][c:4]([CH:9]2[NH:10][C:11](=[O:15])[O:12][CH:13]2[CH3:14])[cH:5][cH:6][c:7]1[F:8].[F:21][c:22]1[cH:23][cH:24][c:25]([CH:28]2[CH2:29][CH2:30][N:31]([CH2:34][CH2:35][CH2:36][NH2:37])[CH2:32][CH2:33]2)[cH:26][cH:27]1.[OH2:56]>>[F:1][c:2]1[cH:3][c:4]([CH:9]2[N:10]([C:41]([NH:37][CH2:36][CH2:35][CH2:34][N:31]3[CH2:30][CH2:29][CH:28]([c:25]4[cH:24][cH:23][c:22]([F:21])[cH:27][cH:26]4)[CH2:33][CH2:32]3)=[O:42])[C:11](=[O:15])[O:12][CH:13]2[CH3:14])[cH:5][cH:6][c:7]1[F:8]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-0286425b8ef14612bf009b67e18cff47
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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