2,6-Difluorobenzoyl isocyanate → HCID 20526046, compound

Participants

Reaction Steps

5.4 g of 3-trifluoromethyl-4-(1,1,2,2-tetrafluoroethoxy)-aniline are placed into 20 ml of abs. ether, and 3.7 g of 2,6-difluorobenzoylisocyanate dissolved in 10 ml of abs. ether are subsequently added dropwise at room temperature. The solid which has precipitated is filtered off with suction after 1 hour; it is then washed with abs. ether and dried in air. Recrystallisation from toluene yields N-[3-trifluoromethyl-4-(1,1,2,2-tetrafluoroethoxy)-phenyl]-N'-(2,6-difluorobenzoyl)-urea having a melting point of 182°-185° C.

Provenance & Evidence