Thionyl Chloride → HCID 178479468, 화합물

HRID 1702609노트

반응식

HRID 1702609 반응식
[ClH:1].[NH:2]([CH2:6][C@H:7]1[CH2:12][CH2:11][C@H:10]([C:13]([OH:15])=O)[CH2:9][CH2:8]1)[C:3]([NH2:5])=[NH:4].S(Cl)([Cl:18])=O>>[ClH:18].[NH:2]([CH2:6][C@H:7]1[CH2:12][CH2:11][C@H:10]([C:13]([Cl:1])=[O:15])[CH2:9][CH2:8]1)[C:3]([NH2:5])=[NH:4]

참가 물질

3

반응물 2

HCID 24386Thionyl ChlorideHCID 178479474HCID 178479474, 화합물

생성물 1

HCID 178479468HCID 178479468, 화합물

실험 절차

A suspension of trans-4-guanidinomethylcyclohexanecarboxylic acid hydrochloride (1.2 g) and thionyl chloride (15 ml) was stirred at room temperature for 3 hours. Thereafter, excess thionyl chloride was removed by distillation under reduced pressure. The residue was washed with anhydrous ethyl ether to obtain trans-4-guanidinomethylcyclohexanecarboxylic acid chloride hydrochloride (1.2 g) as colorless powder.

후처리

  1. customThereafter, excess thionyl chloride was removed by distillation under reduced pressure
  2. washThe residue was washed with anhydrous ethyl ether

출처 및 근거

ORD 기록
ord-d9af0aa0853d4105a0fad7c3b8b7641c
출처 데이터셋
uspto-grants-1982_09
특허 번호
US04348410

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