1-Bromohexadecane → HCID 20525757, compound

HRID 1702669Notes

Reaction equation

HRID 1702669 reaction equation
[NH2:1][C:2]1[CH:14]=[CH:13][C:5]([CH2:6][CH2:7][C:8]([O:10][CH2:11][CH3:12])=[O:9])=[CH:4][CH:3]=1.Br[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31].C(=O)([O-])[O-].[K+].[K+]>CN(C)P(N(C)C)(N(C)C)=O>[CH2:31]([NH:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:6][CH2:7][C:8]([O:10][CH2:11][CH3:12])=[O:9])=[CH:13][CH:14]=1)[CH2:30][CH2:29][CH2:28][CH2:27][CH2:26][CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH3:16]

Participants

5

Reactant 3

HCID 82131-BromohexadecaneHCID 11430Potassium CarbonateHCID 10442595Ethyl 3-(4-aminophenyl)propanoate

Product 1

HCID 20525757HCID 20525757, compound

Reagents, catalysts & solvents 1

HCID 12679HexamethylphosphoramideSolvent

Procedure

In a manner according to Example 1, ethyl p-aminohydrocinnamate is alkylated with 1-bromohexadecane and potassium carbonate in hexamethylphosphoramide, providing ethyl 4-(hexadecylamino)hydrocinnamate.

Sources & evidence

ORD record
ord-48fc0c84fe41425fb53daebc4b2d7ce9
Source dataset
uspto-grants-1982_09
Patent number
US04348399

Reaction notes

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