Ethanol → HCID 20525799, compound

HRID 1702677Notes

Reaction equation

HRID 1702677 reaction equation
[CH2:1]([NH:17][C:18]1[CH:23]=[CH:22][C:21]([CH2:24][C:25](=[O:30])[C:26]([O:28]C)=[O:27])=[CH:20][CH:19]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].[OH-].[K+].C(O)C.O>C(O)(=O)C>[CH2:1]([NH:17][C:18]1[CH:19]=[CH:20][C:21]([CH2:24][C:25](=[O:30])[C:26]([OH:28])=[O:27])=[CH:22][CH:23]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]

Participants

6

Reactant 4

HCID 702EthanolHCID 962WaterHCID 14797Potassium HydroxideHCID 53804060HCID 53804060, compound

Product 1

HCID 20525799HCID 20525799, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A mixture of 5 g. of methyl (4-hexadecylaminophenyl)pyruvate, 5 g. of potassium hydroxide and 50 ml. of a 1:1 ethanol:water solution is heated to 50° for 3 hrs. While hot, the reaction mixture is neutralized with acetic acid and cooled. The precipitate is collected, dried and recrystallized, yielding (4-hexadecylaminophenyl)pyruvic acid.

Workup

  1. additionA mixture of 5 g
  2. temperaturecooled
  3. customThe precipitate is collected
  4. customdried
  5. customrecrystallized

Sources & evidence

ORD record
ord-e131551a74294ddc829f34303a545224
Source dataset
uspto-grants-1982_09
Patent number
US04348399

Reaction notes

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