1-Methoxy-2-propanol → N-tert-Butyl-3-(2-{4-[4-(4-methyl-piperazin-1-ylmethyl)-piperidin-1-yl]-phenylamino}-pyrrolo[2,1-f][1,2,4]triazin-7-yl)-benzenesulfonamide
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[NH:5][S:6](=[O:7])(=[O:8])[c:9]1[cH:10][c:11](-[c:15]2[cH:16][cH:17][c:18]3[cH:19][n:20][c:21]([S:24]([CH3:25])=[O:26])[n:22][n:23]23)[cH:12][cH:13][cH:14]1.[CH3:27][N:28]1[CH2:29][CH2:30][N:31]([CH2:34][CH:35]2[CH2:36][CH2:37][N:38]([c:41]3[cH:42][cH:43][c:44]([NH2:47])[cH:45][cH:46]3)[CH2:39][CH2:40]2)[CH2:32][CH2:33]1.[CH3:57][O:58][CH2:59][CH:60]([OH:61])[CH3:62].[CH:48]([N:49]([CH2:50][CH3:51])[CH:52]([CH3:53])[CH3:54])([CH3:55])[CH3:56]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[NH:5][S:6](=[O:7])(=[O:8])[c:9]1[cH:10][c:11](-[c:15]2[cH:16][cH:17][c:18]3[cH:19][n:20][c:21]([NH:47][c:44]4[cH:43][cH:42][c:41]([N:38]5[CH2:37][CH2:36][CH:35]([CH2:34][N:31]6[CH2:30][CH2:29][N:28]([CH3:27])[CH2:33][CH2:32]6)[CH2:40][CH2:39]5)[cH:46][cH:45]4)[n:22][n:23]23)[cH:12][cH:13][cH:14]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-d88e6d9e237f4586803e3304c743cc70
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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