HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 20525106, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | P,P-Diphenylphosphinic azide | HCID 199401 | — |
| Reactant | HCID 20525116 | HCID 20525116 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 20525106 | HCID 20525106 | — |
Reaction Steps
The reaction of 3-(2-cyanoethylthio)propionic acid and diphenylphosphoryl azide in a solution of triethyl amine and benzene provided a solution comprising 2-(2-cyanoethylthio)ethyl isocyanate (I.R.: 2250 cm-1), which was reacted with 5-fluorouracil to provide 1-[N-[2-(2-cyanoethylthio)ethyl]carbamoyl]-5-fluorouracil substantially in the similar method to that of Example 10.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04349552 |
| Source dataset | uspto-grants-1982_09 |
| ORD ID | ord-56efb58428d4466488393972f7d4e1b4 |
| Source note | uspto-grants-1982_09 |