Methane → HCID 178449239, compound

HRID 1702838Notes

Reaction equation

HRID 1702838 reaction equation
[Cl:1][C:2]1[C:11]([CH3:12])=[N:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1.C.[CH2:14]([NH:18][C:19]([NH2:21])=[S:20])[CH2:15][CH2:16][CH3:17]>CC(C)=O>[ClH:1].[CH3:12][C:11]1[C:2]([S:20][C:19](=[NH:21])[NH:18][CH2:14][CH2:15][CH2:16][CH3:17])=[N:3][C:4]2[C:9]([N:10]=1)=[CH:8][CH:7]=[CH:6][CH:5]=2

Participants

5

Reactant 3

HCID 297MethaneHCID 2362762-Chloro-3-methylquinoxalineHCID 1551919Thiourea, butyl-

Product 1

HCID 178449239HCID 178449239, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent2×

Procedure

2-Chloro-3-methylquinoxaline (3.572 g., 0.02 mole) was dissolved in 50 ml. of acetone treated with Norit and filtered. The filtrate was added to a solution of 2.645 g. (0.02 mole) n-butylthiourea in 25 ml. acetone. After the mixture was stirred at room temperature for 31/2 hours, the solid which had formed was filtered, washed with acetone, then ether and dried to give 4.86 g. (78.2%) of product as an off-white solid, m.p. 118.5°-119.5°.

Workup

  1. filtrationfiltered
  2. additionThe filtrate was added to a solution of 2.645 g
  3. customthe solid which had formed
  4. filtrationwas filtered
  5. washwashed with acetone
  6. dry with materialether and dried
  7. customto give 4.86 g

Sources & evidence

ORD record
ord-faf3c1df77dd44c5919be2c12ed0e054
Source dataset
uspto-grants-1982_09
Patent number
US04349674

Reaction notes

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