Sodium Hydroxide → HCID 12961712, compound

HRID 1702897Notes

Reaction equation

HRID 1702897 reaction equation
C([O:3][C:4](=[O:25])[CH2:5][N:6]1[CH:10]=[C:9]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[N:8]([C:17]2[CH:22]=[CH:21][C:20]([Cl:23])=[CH:19][CH:18]=2)[C:7]1=[O:24])C.[OH-].[Na+]>C(O)C>[Cl:23][C:20]1[CH:21]=[CH:22][C:17]([N:8]2[C:9]([C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=3)=[CH:10][N:6]([CH2:5][C:4]([OH:25])=[O:3])[C:7]2=[O:24])=[CH:18][CH:19]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 12961708HCID 12961708, compound

Product 1

HCID 12961712HCID 12961712, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

13.6 g of [3-(4-chlorophenyl)-2-oxo-4-phenyl-4-imidazolin-1-yl] acetic acid ethyl ester and 1.52 g of NaOH are dissolved in 80 cc. of ethanol and the mixture is stirred at room temperature for 24 hours. The alcohol is distilled off in a vacuum and the residue is dissolved in water. The aqueous solution is shaken with ether, the aqueous phase is acidified with dilute hydrochloric acid and the precipitated acid is separated and dried.

Workup

  1. distillationThe alcohol is distilled off in a vacuum
  2. dissolutionthe residue is dissolved in water
  3. customthe precipitated acid is separated
  4. customdried

Sources & evidence

ORD record
ord-5926d80d62e249f7b26a5b19161b696b
Source dataset
uspto-grants-1982_09
Patent number
US04349684

Reaction notes

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