HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 20524091, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | HCID 70545066 | HCID 70545066 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 20524091 | HCID 20524091 | — |
Reaction Steps
36.2 g N-(2-cyanoethyl)-N-methyl-3-(3-indolyl)propyl amine are hydrogenated at normal pressure and at room temperature with 20 g Raney-nickel catalyst in 400 ml dioxan and 400 ml of a 10% ammonia solution. N-[3-(3-indolyl)propyl]-N-methyl-1,3-diaminopropane is obtained after working up. M.pt of the neutral fumarate: 180°-181° (with decomposition) after crystallization from ethanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04350634 |
| Source dataset | uspto-grants-1982_09 |
| ORD ID | ord-5bf41b3c07e2444abed959a2ee021fd7 |
| Source note | uspto-grants-1982_09 |