Indole → HCID 20524088, compound

HRID 1702927Notes

Reaction equation

HRID 1702927 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=[CH:2]1.[C:10](#[N:13])[CH:11]=[CH2:12]>COC(OC)C>[C:10]([CH2:11][CH2:12][N:1]([CH2:2][CH2:3][C:3]1[C:4]2[C:9](=[CH:8][CH:7]=[CH:6][CH:5]=2)[NH:1][CH:2]=1)[CH3:9])#[N:13]

Participants

4

Reactant 2

HCID 798IndoleHCID 7855Acrylonitrile

Product 1

HCID 20524088HCID 20524088, compound

Reagents, catalysts & solvents 1

HCID 107951,1-DimethoxyethaneSolvent

Procedure

Reaction of 3-[2-methylamino)ethyl]indole with acrylonitrile in dimethoxy-ethane yields the N-(2-cyanoethyl)-N-methyl-2-(3-indolyl)ethylamine which is worked up further directly.

Sources & evidence

ORD record
ord-5d64938ec466472ca3d2a7730e44e4db
Source dataset
uspto-grants-1982_09
Patent number
US04350634

Reaction notes

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