HCID 20497519, compound → HCID 20524256, compound

Participants

Reaction Steps

20 g of 3-amino-2-hydrazino-6-methylquinazolin-4(3H)-one were stirred in 100 ml of 4-aminobutanol at 175° C. for 24 hours and the majority of the 4-aminobutanol was then distilled off under vacuum. The residue was diluted with water to crystallize out the product and the mixture was filtered. The product was washed and dried to obtain 16.2 g of 3-amino-2-(4-hydroxybutylamino)-6-methylquinazolin-4(3H)-one.

Provenance & Evidence