Hydrazine hydrate (1:1) → HCID 178514357, compound

Participants

Reaction Steps

The wet product from Step A was dissolved in a mixture of 90 ml hydrazine hydrate and 900 ml of water and the mixture was stirred at 90°-100° C. until crystallization took place. The mixture was allowed to cool and was filtered. The product was washed with water and methanol and dried to obtain 97.2 g of 2-hydrazino-4-hydroxy-6-nitro-quinazoline in the form of a high melting, orange crystalline solid.

Provenance & Evidence