HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 4-(Methoxycarbonyl)-1-methylpyridin-1-ium iodide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Methyl isonicotinate | HCID 227085 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-(Methoxycarbonyl)-1-methylpyridin-1-ium iodide | HCID 12945487 | 97.2% |
Reaction Steps
700 g of methyl isonicotinate and 1.4 kg of methyl iodide were admixed in 2.0 liters of methanol and the resultant solution was stirred and refluxed for 5 hours. After cooling, the mixture was filtered off and the product was washed with ether and dried to obtain 1.385 kg of 4-methoxycarbonyl-1-methylpyridinium iodide (97.2% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04350697 |
| Source dataset | uspto-grants-1982_09 |
| ORD ID | ord-7233c854730d4f9eb2de66fb6d0e1e1a |
| Source note | uspto-grants-1982_09 |