Tert-Butylamine → HCID 70529867, compound

HRID 1703059Notes

Reaction equation

HRID 1703059 reaction equation
[O:1]1[CH2:3][CH:2]1[CH2:4][O:5][C:6]1[CH:15]=[CH:14][CH:13]=[C:12]2[C:7]=1[CH2:8][C@H:9]([O:27][CH2:28][C:29]([N:31]([CH2:35][CH2:36][CH3:37])[CH2:32][CH2:33][CH3:34])=[O:30])[C@H:10]([O:16][CH2:17][C:18]([N:20]([CH2:24][CH2:25][CH3:26])[CH2:21][CH2:22][CH3:23])=[O:19])[CH2:11]2.[C:38]([NH2:42])([CH3:41])([CH3:40])[CH3:39]>CO>[CH3:39][C:38]([NH:42][CH2:3][CH:2]([OH:1])[CH2:4][O:5][C:6]1[CH:15]=[CH:14][CH:13]=[C:12]2[C:7]=1[CH2:8][C@H:9]([O:27][CH2:28][C:29]([N:31]([CH2:32][CH2:33][CH3:34])[CH2:35][CH2:36][CH3:37])=[O:30])[C@H:10]([O:16][CH2:17][C:18]([N:20]([CH2:24][CH2:25][CH3:26])[CH2:21][CH2:22][CH3:23])=[O:19])[CH2:11]2)([CH3:41])[CH3:40]

Participants

4

Reactant 2

HCID 6385Tert-ButylamineHCID 86738117HCID 86738117, compound

Product 1

HCID 70529867HCID 70529867, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A solution of 1.5 g (0.0029 M) of cis-2,2'-[[1,2,3,4-tetrahydro-5-(oxiranyl-methoxy)-2,3-naphthalenediyl]bis(oxy)]bis-[N,N-dipropylacetamide] in 5 ml of methanol and 20 ml of t-butylamine is stirred at room temperature overnight. The solution is evaporated in vacuo to give 1.7 g of oil. This material is dissolved in ether and extracted with 5% aqueous HCl. The aqueous layer is basified with aqueous NaOH and extracted with ether. The ether is washed (saturated NaCl solution), dried (Na2SO4), filtered and evaporated in vacuo to give the title compound as a dense oil, 1.52 g.

Workup

  1. customThe solution is evaporated in vacuo

Sources & evidence

ORD record
ord-672f3200392c4c639d78cb36d2b90357
Source dataset
uspto-grants-1982_09
Patent number
US04350812

Reaction notes

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