反应详情

A mixture of 16.5 g. of ethyl p-aminobenzoate, 8.55 g. of benzyl bromide and 45 ml. of hexamethylphosphorimide are heated in an oil bath at 110° C. for 20 hours. The mixture is diluted with water, chilled, filtered and the solid washed with water to give tan crystals, m.p. 90°-93° C. A sample is recrystallized from ethanol to give tan crystals, m.p. 96°-97° C.

1. additionA mixture of 16.5 g
2. temperaturechilled
3. filtrationfiltered
4. washthe solid washed with water
5. customto give tan crystals, m.p. 90°-93° C
6. customA sample is recrystallized from ethanol
7. customto give tan crystals, m.p. 96°-97° C.