反应详情

To 240 ml. of 1 M borane in tetrahydrofuran chilled in an ice bath, is added dropwise, 20.4 g. of 4-(2-thienyl)butyric acid in 50 ml. of tetrahydrofuran. After the addition, the mixture is allowed to stand at room temperature for 17 hours and is poured onto ice. After standing, the mixture is extracted with ether, the ether extract washed with water, dried over magnesium sulfate and concentrated in vacuo to give a pale yellow oil.

1. additionis added dropwise
2. additionAfter the addition
3. additionis poured onto ice
4. extractionthe mixture is extracted with ether
5. extractionthe ether extract
6. washwashed with water
7. dry with materialdried over magnesium sulfate
8. concentrationconcentrated in vacuo
9. customto give a pale yellow oil