HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → 3-(2-Pyrimidinyl)-3-aza-6-azoniaspiro[5.5]undecane Chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 1,5-Dichloropentane | HCID 12353 | — |
| Reactant | 1-(2-Pyrimidinyl)piperazine | HCID 88747 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 3-(2-Pyrimidinyl)-3-aza-6-azoniaspiro[5.5]undecane Chloride | HCID 13255620 | — |
Reaction Steps
Reaction of 1-(2-pyrimidinyl)piperazine (16.4 g., 0.1 mole), 1,5-dichloropentane (28.2 g., 0.2 mole) and sodium carbonate (21.2 g., 0.2 mole) in 300 ml. of isopropanol according to the procedure of Example 2 affords the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04351939 |
| Source dataset | uspto-grants-1982_09 |
| ORD ID | ord-79d93dc1146e4cd09dbd559e5f0d8e61 |
| Source note | uspto-grants-1982_09 |