Hydrochloric Acid → HCID 20523998, compound

HRID 1703359Notes

Reaction equation

HRID 1703359 reaction equation
C([O:3][C:4]([CH2:6][CH:7]([Cl:16])[CH2:8][C:9]([Cl:15])([Cl:14])[C:10]([Cl:13])([F:12])[F:11])=[O:5])C.Cl>>[Cl:16][CH:7]([CH2:8][C:9]([Cl:14])([Cl:15])[C:10]([Cl:13])([F:11])[F:12])[CH2:6][C:4]([OH:5])=[O:3]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 53680012HCID 53680012, compound

Product 1

HCID 20523998HCID 20523998, compound

Procedure

303.9 g of 2,4,4,5-tetrachloro-5,5-difluoropentane-1-carboxylic acid ethyl ester and 900 ml of a 22% aqueous hydrochloric acid are heated at 95°-100° C. for 20 hours. After cooling, the oily suspension obtained is purified, in the customary manner, by means of an ether extraction, bicarbonate extraction and ether extraction of the acidified bicarbonate solution. The yield is 206.9 g (75% of theory of 2,4,4,5-tetrachloro-5,5-difluoropentane-1-carboxylic acid in the form of a clear liquid, which boils at 107°-108° C./25 Pa.

Workup

  1. temperatureAfter cooling
  2. customthe oily suspension obtained
  3. customis purified, in the customary manner, by means of an ether extraction, bicarbonate extraction and ether extraction of the acidified bicarbonate solution

Sources & evidence

ORD record
ord-b23542f821b941faa9de60f2ce9d7aa1
Source dataset
uspto-grants-1982_09
Patent number
US04351961

Reaction notes

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