Sodium hydride → HCID 54150769, compound

HRID 1703421Notes

Reaction equation

HRID 1703421 reaction equation
C1(S([CH2:10][CH2:11][CH2:12][CH:13]2[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][C:14]2=O)(=O)=O)C=CC=CC=1.[H-].[Na+]>C(N)CN>[C:13]12[CH2:12][CH2:11][CH:10]=[C:14]1[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH:24]=2

Participants

4

Reactant 2

HCID 24758Sodium hydrideHCID 205012032-[3-(Benzenesulfonyl)propyl]cyclododecan-1-one

Product 1

HCID 54150769HCID 54150769, compoundYield 75%

Reagents, catalysts & solvents 1

HCID 3301EthylenediamineSolvent

Procedure

0.720 g (2 mmole) of 2-(3-phenylsulfonyl-prop-1-yl)-cyclododecanone, 0.144 g (6 mmole) of sodium hydride and 10 ml of ethylene-diamine were heated at 100° for 4 hours, then cooled, extracted and finally distilled as indicated hereinabove to afford the desired compound in a 75% yield.

Workup

  1. temperaturecooled
  2. extractionextracted
  3. distillationfinally distilled

Sources & evidence

ORD record
ord-b6d76ba0799b40a38e1eeb045c575f27
Source dataset
uspto-grants-1982_09
Patent number
US04351977

Reaction notes

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