Potassium Carbonate → HCID 131711319, compound

Temperature

10 °C

134.1 g (one mole) of L-malic acid are dissolved in 400 ml of water, and 84.3 g (0.61 mole) of potassium carbonate are added to the L-malic acid solution under stirring. The solution (pH 4.4) is concentrated under reduced pressure at 60° C. to make the total volume thereof about 250 ml. The concentrated aqueous solution is gradually cooled to 10° C. Then, the mixture thus obtained (i.e., the mixture of the concentrated aqueous solution and crystals precipitated) is stirred at the same temperature for 2 hours. After stirring, the mixture had a pH of 5.5. The crystalline precipitates are collected by filtration, washed with an aqueous 80% methanol solution and dried at 35° C. in air for 24 hours. 136.6 g of monopotassium L-malate monohydrate are obtained as crystals. Yield: 71.8% The product loses its intramolecular water at 98° to 100° C. and decomposes at 184° to 185° C.

1. concentrationThe solution (pH 4.4) is concentrated under reduced pressure at 60° C.
2. customThen, the mixture thus obtained (i.e.
3. additionthe mixture of the concentrated aqueous solution and crystals
4. customprecipitated)
5. stirringis stirred at the same temperature for 2 hours
6. stirringAfter stirring
7. customThe crystalline precipitates
8. filtrationare collected by filtration
9. washwashed with an aqueous 80% methanol solution
10. customdried at 35° C. in air for 24 hours

ORD record

ord-02d2b84c33c54de3a3d85d2579f0dfa3

Source dataset

uspto-grants-1978_11

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US04124636