Diethylamine → HCID 162165, compound

HRID 1703578Notes

Reaction equation

HRID 1703578 reaction equation
Cl[CH2:2][CH2:3][O:4][C:5](=[C:12]1[CH:17]2[CH2:18][CH:14]3[CH:15]([CH2:16]2)[CH:13]13)[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.[CH2:19]([NH:21][CH2:22][CH3:23])[CH3:20]>C1C=CC=CC=1>[CH2:19]([N:21]([CH2:22][CH3:23])[CH2:2][CH2:3][O:4][C:5](=[C:12]1[CH:17]2[CH2:18][CH:14]3[CH:15]([CH2:16]2)[CH:13]13)[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)[CH3:20]

Participants

4

Reactant 2

HCID 8021DiethylamineHCID 53965375HCID 53965375, compound

Product 1

HCID 162165HCID 162165, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

A solution of 14 g. (53.6 mMol) of β-chloroethyl-{α-[tricyclo-(2.2.1.02.6)hept-3-ylidene]-benzyl}-ether and 20 g. (0.273 mol) of diethyl amine in 130 ml. of benzene was heated for 5 hours to 140° C. in a 0.5 liter autoclave. After cooling, the diethyl amine hydrochloride was filtered off under suction, benzene and diethyl amine distilled off in vacuo and the residue left subjected to acid-alkaline working up. The basic fraction was fractionated in vacuo.

Workup

  1. temperatureAfter cooling
  2. filtrationthe diethyl amine hydrochloride was filtered off under suction, benzene and diethyl amine
  3. distillationdistilled off in vacuo
  4. waitthe residue left

Sources & evidence

ORD record
ord-38d03486f57f447086eea619e617aee2
Source dataset
uspto-grants-1978_11
Patent number
US04124716

Reaction notes

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