反应详情

This product is prepared by the reaction of 2-bromo-5-chlorosulfonyl benzoic acid with excess thiomorpholine in methylene chloride. The product, m.p. 195°-197.5° C., is purified by solution in aqueous sodium hydroxide, crystallization by acidifying the basic solution, and recrystallization from acetone-hexane.

1. customThe product, m.p. 195°-197.5° C., is purified by solution in aqueous sodium hydroxide
2. customcrystallization
3. customthe basic solution, and recrystallization from acetone-hexane