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HRID1703733

反应详情

EQUATION

反应方程式

HRID 1703733 的结构方程式

REACTANTS

反应物

2
结构：[Cl-].[NH4+]
HCID25517

未命名化合物

结构：CC(=O)OC[C@H]1O[C@@H](n2cnc(C#N)n2)[C@H](OC(C)=O)[C@@H]1OC(C)=O
HCID13456801

1-(2,3,5-Tri-O-acetyl-beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carbonitrile

C14H16N4O7

PRODUCTS

生成物

1
结构：Cl.N=C(N)c1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)n1
HCID451447

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：N
溶剂HCID222

Ammonia gas

H3N

PROCEDURE

实验过程

A mixture of 3-cyano-1-(2,3,5-tri-O-acetyl-β -D-ribofuranosyl)-1,2,4-triazole (7.04 g., 20.0 mmole) ammonium chloride (1.07 g., 20.0 mmol) and anhydrous ammonia (150 ml.) was heated in a bomb at 85° for 18 hours. After removal of excess ammonia, the residue was crystallized from acetonitrile-ethanol to provide 5.30 g. (95%) of product with M.P. 177°-179° dec.

WORKUP

后处理

  1. temperaturewas heated in a bomb at 85° for 18 hours
  2. customAfter removal of excess ammonia
  3. customthe residue was crystallized from acetonitrile-ethanol
  4. customto provide 5.30 g